000 03429cam a22003614a 4500
001 2001035238
003 DLC
005 20190729102618.0
008 010411s2003 enka b 001 0 eng
010 _a 2001035238
020 _a052164285X (hardcover)
020 _a052164481X (pbk.)
040 _aDLC
_cDLC
_dDLC
042 _apcc
049 _aEY8Z
050 0 0 _aQH506
_b.E66 2003
082 0 0 _a612
_221
100 1 _aEpstein, R. J.
245 1 0 _aHuman molecular biology :
_ban introduction to the molecular basis of health and disease /
_cRichard J. Epstein.
260 _aCambridge, UK ;
_aNew York :
_bCambridge University Press,
_c2003.
300 _axxxi, 623 p. :
_bcol. ill. ;
_c29 cm.
500 _a"Select glossary of confusing terms and abbreviations" -- p. [xxvii]
504 _aIncludes bibliographical references and index.
505 0 _aIntroduction - a disease for every gene? PART I. From Molecular Biology to Human Genetics: Ch. 1. Biomolecular evolution -- Ch. 2. Chromatin and chromosomes -- Ch. 3. Gene expression -- Ch. 4. RNA processing and translation -- Ch. 5. Protein structure and function. PART II. From Molecular Genetics to Human Biochemistry: Ch. 6. Nutrition and energy -- Ch. 7. Membranes and channels -- Ch. 8. Cell surface receptors and antigen recognition -- Ch. 9. Adhesion molecules and the extracellular matrix -- Ch. 10. Cytoskeletal proteins and molecular motors. PART III. From Molecular Biochemistry to Human Cell Biology: Ch. 11. Signal transduction -- Ch. 12. Bioactive lipids and Inflammatory cytokines -- Ch. 13. Hormones and growth factors -- Ch. 14. Hemopoietins, angiogenins and vasoactive mediators -- Ch. 15. Cell cycle control, apoptosis and ageing. PART IV. From Molecular Cell Biology to Human Physiology: Ch. 16. Development -- Ch. 17. Metabolism -- Ch. 18. Blood -- Ch. 19. Immunity -- Ch. 20. Neurobiology. PART V. From Molecular Physiology to Human Molecular Biology: Ch. 21. Genetic experimental systems -- Ch. 22. Gene and protein analysis -- Ch. 23. Genetic engineering, gene mapping and gene testing -- Ch. 24. Gene knockouts, transgenics, and cloning -- Ch. 25. Gene therapy and recombinant DNA technology.
520 _aPublisher description: Human Molecular Biology is an introduction to the molecular basis of health and disease for the new generation of life scientists and medical students. By integrating cutting-edge molecular genetics and biochemistry with the latest clinical information, the book weaves a pattern which unifies biology with syndromes, genetic pathways with developmental phenotypes, and protein function with drug action. From the origins of life to the present day, a narrative is traced through the workings of genomes, cells and organ systems, culminating in linking of laboratory technologies to future research horizons. Lavishly illustrated throughout with two-colour diagrams and full colour clinical pictures, this text brings the complexities and breadth of human molecular biology clearly to life. This seamless account breaks through the boundaries between molecular biology and medicine, and leads the reader on to a new dimension where the biological basis of health and disease is inescapably molecular.
650 0 _aMolecular biology.
650 0 _aPathology, Molecular.
650 0 _aHuman biology.
948 _au161225
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