000			02837cam a2200313 i 4500
001			ocm1252411662
005			20250109090122.0
008			210522s2022 mau b 001 0 eng d
020			_a0262543885 _q(paperback)
020			_a9780262543880 _q(paperback)
035			_a(OCoLC)1252411662
035			_a(OCoLC)on1252411662
040			_aYDX _beng _erda _cYDX _dBDX _dUKMGB _dOCLCF _dOCLCO _dMYG _dBKL _dUNBCA _dOCLCO _dSCO _dMiTN _dUtOrBLW
050	1	4	_aQH438.7 _b.G74 2021
100	1		_aGreely, Henry T.,
245	1	0	_aCRISPR people : _bthe science and ethics of editing humans / _cHenry T. Greely.
264		1	_aCambridge, Massachusetts : _bThe MIT Press, _c[2021]
264		4	_c©2021
300			_axiii, 380 pages ; _c18 cm
336			_atext _btxt _2rdacontent.
337			_aunmediated _bn _2rdamedia.
338			_avolume _bnc _2rdacarrier.
504			_aIncludes bibliographical references (pages 299-369) and index.
505	0	0	_tJust what did He Jiankui do? -- _tHuman germline genome editing : what is it? -- _tCRISPR : what is it, why is it important, and who will benefit from it? -- _tEthics discussions of CRISPR'd babies before He -- _tThe law of CRISPR'd babies before He -- _tThe He experiment revealed -- _tThe world reacts : and so does China -- _tWho knew what when? Revelations of pre-summit knowledge -- _tAssessing the He experiment -- _tResponses -- _tIs human germline genome editing inherently bad? -- _tCould human germline genome editing sometimes be bad? -- _tJust how useful is human germline genome editing? -- _tHow to test human germline genome editing -- _tThe big decisions : and how to make them.
520			_a"In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos -- as dramatic a development in genetics as the 1996 cloning of Dolly the sheep. In this book, Hank Greely tells the fascinating story of this human experience and its consequences. Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention. The two babies, nonidentical twin girls, were the first 'CRISPR'd' people ever born (CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, is a powerful gene-editing method). Greely considers the lessons to be drawn both from these CRISPR'd babies and, more broadly, from 'germline editing' that can be passed on from one generation to the next. He doesn't mince words, describing He's experiment as grossly reckless, irresponsible, immoral, and illegal. We should consider the implications carefully before we proceed." -- _cBack.
650		0	_aCRISPR (Genetics)
650		0	_aGene editing _xMoral and ethical aspects.
650		0	_aHuman beings _xGenome mapping _xMoral and ethical aspects.
999			_c522520 _d522520