TY - BOOK AU - Prasad,Vinayak K. AU - Cifu,Adam S. TI - Ending medical reversal: improving outcomes, saving lives SN - 9781421417721 (hardcover : alk. paper) AV - R733 .P73 2015 U1 - 615.5 23 PY - 2015/// CY - Baltimore PB - Johns Hopkins University Press KW - 0 KW - Medical care KW - Therapeutics KW - Clinical trials KW - Evidence-based medicine N1 - Includes bibliographical references and index; What is medical reversal? -- Subjective outcomes : why feeling better is often misleading -- Surrogate outcomes -- Screening tests -- System failure -- Finding flawed therapies on our own -- The frequency of medical reversal -- The harms of medical reversal : today's patients, tomorrow's patients and the healthcare field -- A primer in evidence based medicine : what is evidence in medicine? -- What really got you better : when evidence gets complicated -- Scientific progress, revolution, and medical reversal -- Sources of flawed data -- Why are we so attracted to flawed therapies? -- Medical education : a very good place to start -- Academic medicine -- Reforming the system : the burden of proof and nudging our way past reversal -- How not to become a victim of reversal -- Beyond dogma : when randomized trials are unnecessary ER -