TY - BOOK AU - Stockwell,Brent R. TI - The quest for the cure: the science and stories behind the next generation of medicines SN - 9780231152129 (cloth : acidfree paper) AV - RM301.25 .S76 2011 U1 - 615/.19 22 PY - 2011/// CY - New York PB - Columbia University Press KW - Drug development KW - Drugs KW - Design KW - Proteins KW - Metabolism N1 - Includes bibliographical references (p. [229]-249) and index; The drug discovery crisis -- A new science of molecules -- The birth of the first cancer drugs -- A new company creating drug cocktails -- The undruggable RAS protein -- The druggable genome -- Peering inside proteins -- The nature of interactions between proteins -- Blocking protein-protein interactions -- A revolution in peptide synthesis -- A vast array of drug candidates -- Moving outside the small molecule box -- Accelerating the arrival of next generation drugs ER -