Stockwell, Brent R.

The quest for the cure : the science and stories behind the next generation of medicines / Brent R. Stockwell. - New York : Columbia University Press, 2011. - xviii, 265 p. : ill. ; 22 cm.

Includes bibliographical references (p. [229]-249) and index.

The drug discovery crisis -- A new science of molecules -- The birth of the first cancer drugs -- A new company creating drug cocktails -- The undruggable RAS protein -- The druggable genome -- Peering inside proteins -- The nature of interactions between proteins -- Blocking protein-protein interactions -- A revolution in peptide synthesis -- A vast array of drug candidates -- Moving outside the small molecule box -- Accelerating the arrival of next generation drugs.

9780231152129 (cloth : acidfree paper) 9780231525527 (ebook)

2010053573


Drug development.
Drugs--Design.
Proteins--Metabolism.

RM301.25 / .S76 2011

615/.19

QV 744