The quest for the cure : the science and stories behind the next generation of medicines /
Brent R. Stockwell.
- New York : Columbia University Press, 2011.
- xviii, 265 p. : ill. ; 22 cm.
Includes bibliographical references (p. [229]-249) and index.
The drug discovery crisis -- A new science of molecules -- The birth of the first cancer drugs -- A new company creating drug cocktails -- The undruggable RAS protein -- The druggable genome -- Peering inside proteins -- The nature of interactions between proteins -- Blocking protein-protein interactions -- A revolution in peptide synthesis -- A vast array of drug candidates -- Moving outside the small molecule box -- Accelerating the arrival of next generation drugs.